Jane F. Ferguson, PhD

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Associate Professor of Medicine, Division of Cardiovascular Medicine

Research Description

My research focuses on the genetics of cardiometabolic diseases, with a particular focus on functional genomics and clinical translation. I am interested in the interactions between genetic and environmental factors in disease development, and in the use of evoked phenotypes as a tool for genomic discovery. My current research projects include: 1) Understanding the genomic determinants of febrile illness; 2) The role of long-chain polyunsaturated fatty acids in adipose inflammation; 3) The interaction between diet and the microbiome in cardiometabolic risk; 4) The effect of ventricular assist device implantation on pericardial adipose inflammation.

Brief Description

Dr. Jane Ferguson joined the Vanderbilt faculty in October 2014 as an Assistant Professor of Medicine in the Division of Cardiovascular Medicine. Her research focuses on the genetics of cardiometabolic diseases with a particular focus on functional genomics and clinical translation. She is interested in the interactions between genetic and environmental factors in disease development and in the use of evoked phenotypes as a tool for genomic discovery, utilizing discovery platforms across the “omics” spectrum. Her current research projects include: 1) Understanding the genomic determinants of febrile illness; 2) The role of long-chain polyunsaturated fatty acids in adipose inflammation; and 3) the interaction between diet and the microbiome in cardiometabolic risk. Originally from Ireland, she completed her undergraduate degree in Human Genetics at Trinity College Dublin and received her PhD in nutrigenomics from University College Dublin, where her thesis work focused on gene-nutrient interactions in the Metabolic Syndrome. Dr. Ferguson moved to the U.S. in 2009 for postdoctoral training at the University of Pennsylvania, where her research focused on translational genomics of cardiovascular disease.

Email
jane.f.ferguson@vumc.org

Education

PhD - University College Dublin