Wilson Lab News and Events

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Virtual CMIC Seminar Series.

Speaker: M. Blanca Piazuelo MD, Research Associate Professor, Division of Gastroenterology, Hepatology, and Nutrition

Title: “The Colombian chemoprevention trial. Twenty-year follow-up of a cohort of patients with gastric precancerous lesions”

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The findings, reported in the March 12 issue of Proceedings of the National Academy of Sciences, support further studies of DFMO for the prevention of stomach cancer, the third leading cause of cancer deaths worldwide.

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Wilson and his colleagues began using cell cultures to explore the enzymatic pathways that produce nitric oxide and alternative products. Their studies led them to molecules called polyamines, which are produced by the enzyme ornithine decarboxylase (ODC) and which have been shown to be both detrimental and beneficial to cells, depending on the context.

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