Photo
Language
English
Title and Department
Associate Professor of Medicine
Department of Medicine, Division of Infectious Diseases
Professional bio
Jennifer Gaddy, PhD, is an Assosicate Professor of Medicine in the Division of Infectious Diseases within the Department of Medicine at Vanderbilt University Medical Center.
Her research interests are focused on determining how bacteria interact with host cells and evade the immune system. In particular, her work has focused on mechanisms of metal homeostasis that alter bacterial virulence and determining how prokaryotic pathogens circumnavigate nutritional immunity within the vertebrate host. Dr. Gaddy’s research has revealed that nutrient iron and zinc availability affects the production and secretion of toxins by the gastric pathogen Helicobacter pylori. She employs numerous methods in her research including bacteriology, molecular biology, genetics, and biochemical, immunological, and high resolution imaging techniques.
Dr. Gaddy was granted a Career Development Award (Level 2) from the Department of Veterans Affairs to pursue her research into the metal-dependent regulation of the Helicobacter pylori cag-Type IV secretion system that secretes the oncogenic cytotoxin, CagA.
Her research interests are focused on determining how bacteria interact with host cells and evade the immune system. In particular, her work has focused on mechanisms of metal homeostasis that alter bacterial virulence and determining how prokaryotic pathogens circumnavigate nutritional immunity within the vertebrate host. Dr. Gaddy’s research has revealed that nutrient iron and zinc availability affects the production and secretion of toxins by the gastric pathogen Helicobacter pylori. She employs numerous methods in her research including bacteriology, molecular biology, genetics, and biochemical, immunological, and high resolution imaging techniques.
Dr. Gaddy was granted a Career Development Award (Level 2) from the Department of Veterans Affairs to pursue her research into the metal-dependent regulation of the Helicobacter pylori cag-Type IV secretion system that secretes the oncogenic cytotoxin, CagA.