Reducing the human reservoir of M. tuberculosis infection through early TB detection, treatment and prevention are vital to reducing the global burden of TB.

Active Projects

  • Short-course rifapentine for TB prevention for all: clinical pharmacology matters; PI – Kelly Dooley; NIH R37AI184117
  • TBTC Study 37, ASTEROID (Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine given Daily for LTBI); Nashville, TN; PI – Timothy Sterling; CDC
  • Immune-mediated adverse drug reactions to HIV and TB treatments in South Africa: predict, prevent and improve long-term outcomes (IMARI SA study); South Africa; PIs - Elizabeth Phillips, Graeme Meintjes (South Africa); NIH R01AI152183
  • TB Treatment and Prevention at the Metro Nashville Public Health TB Clinic

Completed Projects

  • Multi-level and Intersectional Stigma and other Social determinant Effects on TB case Detection, care, and treatment outcomes: The MISSED TB Outcomes Study; PIs - Carolyn Audet; Desmond Tutu Foundation
  • Innovative Modelling for predicting TB treatment outcomes in global cohorts; PIs Bruno Andrade (Brazil), Timothy Sterling; CRDF Global
  • Patient-centered intervention to prevent TB among children less than 5 years old; Peru; PI – Larissa Otero (Peru); NIH K43TW011137
  • Tuberculosis Trials Consortium (TBTC); Peru; PIs – Timothy Sterling, April Pettit; CDD
  • Tuberculosis Epidemiology Studies Consortium (TBESC); Nashville, TN; PIs – April Pettit, Timothy Sterling; CDC
  • Characterizing the impact of HIV disease severity in prediction models for tuberculosis treatment outcomes; Nashville, TN; PI – Lauren Peetluk; NIH F31AI152614