Rapid and accurate diagnosis is critical for timely initiation of TB treatment, but many people with TB (or TB symptoms) do not have access to adequate initial diagnosis. New tools and diagnostics are needed that can accurately diagnosis TB disease and be utilized in settings across the globe.

Active Projects

  • Evaluation Of The Role Of Tongue Swabs To Optimize Tutt Implementation - An Observational Study (Tuttplus); PI – Ribka Berhanu; Gates Foundation
  • Sputum PCR-based test (Truenat) for the diagnosis of TB; Brazil; PIs – Afranio Kritski (Brazil)

Completed Projects

  • A 100-fold more sensitive TB diagnostic based on magnetic concentration and "coffee ring" formation; PIs – David Wright and Rick Haselton; NIH R01AI135937
  • Novel urine lipoarabinomannan (LAM) test; Brazil; PIs - David Wright, Micaella Jorge, Valeria Rolla, Adriano Gomes
  • Urine TB diagnostic by amplicon reconstruction for PCR detection of DNA fragments; PI – Rick Haselton; NIH R21AI152497