Title and Department
Associate Professor of Medicine
Department of Medicine
Clinical Pharmacology
Vanderbilt University Medical Center
Professional bio

Jonathan D. Mosley, MD, PhD, is an Associate Professor in the Division of Clinical Pharmacology, Department of Medicine, at Vanderbilt University Medical Center. He is a clinically trained scientist with a professional background in mathematics, information systems development and epidemiology and doctoral training in molecular and mouse models of mammary gland tumorigenesis.

Dr. Mosley's research interests include identifying translational applications of measures polygenic variation into clinical practice in order to improve health care delivery, reduce unnecessary health care utilization and improve risk stratification. This work typically leverages data from electronic health record data sources and epidemiological studies. One focus is on "benign" genetic variation that may cause healthy individuals to have outlying trait values that are misinterpreted as pathology in a clinical setting. These individuals may be subjected to unnecessary testing and evaluations. Dr. Mosley is interested in using genetics to prospectively identify these individuals in order to prevent unnecessary clinical investigations. His content areas of focus include metabolomics, proteomics and cardiac phenotypes and other diseases.