The primary goal of the Training Program in Quantitative Ocular Genomics (TPQOG) is to support predoctoral and postdoctoral training at the intersection of quantitative genomics and ocular disease. Complex genetic ocular diseases, such as age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy, account for significant morbidity in the U.S. and worldwide. This training grant seeks to fund research trainees who are focused on using computational genomic analyses, supported by highly detailed ocular phenotyping, to better understand eye disease pathogenesis and to develop powerful new screening and treatment tools for these conditions. The training program is well positioned to take full advantage of unique resources at Vanderbilt, such as BioVU, the institution’s de-identified DNA database with associated electronic medical records, the VEI’s focused initiative in personalized medicine in ophthalmology, and numerous high-throughput Vanderbilt and VUMC core facilities. Trainees in the program are developing creative collaborations, designing novel genetic analysis methods, and developing new gene therapy treatment modalities.