Publications

  1. Vickers, K.C., Palmisano, B.T., Shoucri, B.M., Shamburek, R.D., & Remaley, A.T. (2011). MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nature Cell Biology. 13(4), 423-433. PMID:21423178 PMCID:3074610 #, ^ Citations: 3216.

    # Editor’s Choice, Riddihough, G. (2011). Have miRNA, Will Travel. Science 8, 150-151.
    ^     Research Highlights, Elsner, M. (2011). MicroRNA shuttles. Nature Biotechnology. 29, 410.

  2. Vickers, K.C., Shoucri, B.M., Levin, M.G., Wu, H., Pearson, D.S., Osei-Hwedieh, D., Collins, F.S., Remaley, A.T., Sethupathy, P. (2013). MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia. Hepatology. 57(2):533-542. PMID:22777896 PMCID:3470747. Citations: 273. #.

    # Commentary: Fernández-Hernando, C. (2013). Emerging role of microRNAs in the regulation of lipid metabolism. Hepatology. 57(2):432-434. PMID:22806606

  3. *Tabet, F., *Vickers, K.C., Cuesta Torres, L.F., Wiese, C.B., Shoucri, B.M., Lambert, G., Catherinet, C., Prado-Lourenco, L., Levin, M.G., Thacker, S., Sethupathy, P., Barter, P.J., Remaley, A.T., Rye, K.A. (2014). HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells. Nature Communications. 5:3292. PMID:24576947 PMCID4189962 *Co-First Authors. Citations: 453. #

    # Commentary: Fernández-Hernando, C. (2014). Antiatherogenic Properties of High-Density Lipoprotein-Enriched MicroRNAs. Arteriosclerosis, Thrombosis, and VascularBiology. 34(6):e13-4. PMID:24764456. PMCID:4288964

  4. Vickers, K.C.,Landstreet, S.R., Levin, M.G., Shoucri, B.M., Toth, C.L., Taylor, R.C., Palmisano, B.T., Tabet, F., Cui, H.L., Rye, K.A., Sethupathy, P., Remaley, A.T. (2014). MicroRNA-223 Coordinates Cholesterol Homeostasis. Proceedings of the National Academy of Sciences. 111(40):14518-14523. PMID:25246565 PMCID:PMC4210029. Citations: 294. #

    # Commentary: Nishi, H., Fisher, E.A. (2015). Cholesterol Homeostasis Regulation by miR-223: Basic Science Mechanisms and Translational Implications. Circulation Research. 116(7):1112-1114. PMID:25814681

  5. Allen, R.M., Zhao, S., Ramirez-Solano, M.A., Michell, D.L., Wang, Y., Shyr, Y., Sethupathy, P., Linton, M.F., Graf, G.A., Sheng, Q., Vickers, K.C. (2018). Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins. Journal of Extracellular Vesicles.7(1):1506198.PMID:30128086 PMCID:PMC6095027. Citations: 73.
  6. Wiese, C.B., Zhong, J., Xu, Z., Zhang, Y., Ramirez-Solano, M., Guo, Y., Zhu, W., Landstreet, S., Linton, M.F., Kon, V., Vickers, K.C. (2019). Dual inhibition of endothelial miR-92a-3p and miR-489-3p reduces renal injury-associated atherosclerosis. Atherosclerosis. 282:121-131. PMID:30731284. Citations: 48.
  7. Sedgeman, L.R., Beysen, C., Ramirez-Solano, M., Michell, D.L., Sheng, Q., Zhao, S., Turner, S.M., Linton, M.F., Vickers, K.C. (2019). Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion Scientific Reports. 9(1):3803. PMID:30846744 PMCID:PMC6405899. Citations: 42.
  8. Hennessy, E.J., van Solingen, C., Scacalossi, K.R., Ouimet, M., Afonso, M.S., Prins, J., Koelwyn, G.J., Ramkhelawon, B., Carpenter, S., Busch, A., Chernogubova, E., Matic, L.P., Hedin, U., Maegdefessel, L., Caffrey, B.E., Hussein, M.A., Ricci, E.P., Temel, R.E., Garabedian, M.J., Berger, J.S., Vickers, K.C., Teupser, D., Holdt, L.M., Moore, K.J. (2019). The long noncoding RNA CHROME regulates cholesterol homeostasis in primates. Nature Metabolism. 1;98–110. PMID:31410392 NIHMSID:NIHMS1509876. Citations: 123. ^
    ^ Commentary: Sallam, T., Tontonoz, P. (2019). Lnc-ing microRNA activity to atheroprotection. Nature Metabolism. 1;10-11.
  9. Tao, H., Yancey, P.G., Blakemore, J.L., Zhang, Y., Ding, L., Jerome, W.G., Brown, J.D., Vickers, K.C., Linton, M.F. (2021). Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis. J Clin Invest. 131(7):e94229. PMID:33661763. Citations: 53.
  10. Abner, J.J., Franklin, J.L., Clement, M.A., Hinger, S.A., Allen, R.M., Liu, X., Kellner, S., Wu, J., Karijolich, J., Liu, Q., Vickers, K.C., Dedon, P., Weaver, A.M., Coffey, R.J., Patton, J.G. (2022). Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences. Heliyon.7(12):e08519. PMID: 34934837. PMCID:PMC8654799. Citations: 13.
  11. Michell, D.L., Allen, R.M., Cavnar, A.B., Contreras, D.M., Yu, M., Semler, E.M., Massick, C., Raby, C.A., Castleberry, M., Ramirez, M.A., Zhu, W., May-Zhang, L., Ifrim, A., Carr, J.J., Terry, J.G., Schwendeman, A., Davies, S.S., Sheng, Q., Linton, M.F., Vickers, K.C. (2022) Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions. J Biol Chem. 298(6):101952. PMID:35447119. PMCID: PMC9133651. Citations: 7.
  12. Allen, R.M., Michell, D.L., Cavnar, A.B., Zhu, W., Makhijani, N., Contreras, D.M., Raby, C.A., Semler, E.M., DeJulius, C., Castleberry, M., Zhang, Y., Ramirez-Solano, M., Zhao, S., Duvall, C., Doran, A.C., Sheng, Q., Linton, M.F., Vickers, K.C.  (2022). LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8. Nat Cell Biol. 24(12):1701-1713. PMID:36474072. NIHMSID:NIHMS1856093. Citations: 17. ^
    ^ Editorial: Ben-Aicha, S., Ibañez, B. (2023). LDL's unexpected travel partners in the road to atherosclerosis. Cardiovasc Res. 119(13):e146–e148. PMCID:PMC10597615
  13. Castleberry, M., Raby, C.A., Ifrim, A., Shibata, Y., Matsushita, S., Ugawa, S., Miura, Y., Hori, A., Miida, T., Linton, M.F., Michell, D.L., Tsujita, M., Vickers, K.C.  (2023).  High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages. Journal of Lipid Research. 100328. PMID:36626966. Citations: 2.
  14. Wu, Q., Sheng, Q., Michell, D., Ramirez-Solano, M., Posey, O., Phothisane, A., Shaik, S., Vickers, K.C., Ormseth, M.J. (2024) Anti-Inflammatory Effect of High-Density Lipoprotein Blunted by Delivery of Altered MicroRNA Cargo in Patients With Rheumatoid Arthritis. Arthritis Rheumatol. 76(5):684-695.PMCID:PMC11045320,PMID:38111131
  15. Hoogenboezem, E.N., Patel , S.S., Lo, J.H., Cavnar, A.B., Babb, L.M., Francini, N., Gbur, E.F., Patil, P., Colazo, J.M., Michell, D.L., Sanchez, V.M., McCune, J.T., Ma, J., DeJulius, C.R., Lee, L.H., Rosch, J.C., Allen, R.M., Stokes, L.D., Hill, J.L., Vickers, K.C., Cook, R.S., Duvall, C.L. (2024). Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy. Nat Comm. 21;15(1):1581. PMID: 38383524 PMCID: PMC10881965 DOI: 10.1038/s41467-024-45609-0. Citations: 3.
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