Featured Publications

2020-2025

• Bejoy, J.; Welch, R.C.; Qian, E.S.; Williams, F.M.; Gibson-Corley, K.N.; Wilson. M.H.; Paragas, N.; and Woodard, L.E. Urine-derived stem cells display homing, incorporation, and regeneration in human organoid and mouse models of acute kidney injury. Molecular Therapy. Online ahead of print, Mar 28, 2025.
• Hartert, J.H. and Woodard, L.E. Chapter: Nonviral genome modification strategies for gene therapy: transposon, integrase, and nuclease systems. Almeida-Porada, G. and Atala, A. Ed. Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, 5th ed.; CRC Press: Boca Raton, submitted July 2024.
• Bejoy, J.; Farry, J.M.; Qian, E.S.; Dearing, C.; Ware, L.; Bastarache, J.; and Woodard, L.E. Ascorbate protects human kidney organoids from damage induced by cell-free hemoglobin. Disease Models and Mechanisms. Dec 1, 2023, 16(12):dmm050342.
• Kenigsberger, Z.; Welch, R.C.; Bejoy, J.; Williams, F.M.; Veach, R.A.; Jarrett, I.; Thompson, T.K.; Wilson, M.H.; and Woodard, L.E. Genome engineering of human urine-derived stem cells to express lactoferrin and deoxyribonuclease. Tissue Engineering Part A. June 2, 2023, 29(13-14):372-383.
• Bejoy, J.; Farry, J.M.; Peek, J.L.; Cabatu, M.C.; Williams, F.M.; Welch, R.C.; Qian, E.S.; and Woodard, L.E. "Podocytes derived from human induced pluripotent stem cells: characterization, comparison, and modeling of diabetic kidney disease." Stem Cell Res Ther. 2022, 13(1):355.”
• Bejoy, J.; Qian, E.S.; and Woodard, L.E. "Tissue Culture Models of AKI: From Tubule Cells to Human Kidney Organoids." J Am Soc Nephrol. 2022, 33(3): 487-501.
• Bejoy, J.; Qian, E.S.; and Woodard, L.E. Tissue Culture Models of AKI: From Tubule Cells to Human Kidney Organoids. J Am Soc Nephrol. 2022, 33(3): 487-501.
• Bejoy, J.; Qian, E.S.; and Woodard, L.E. "Accelerated protocol for the differentiation of podocytes from human pluripotent stem cells." STAR Protoc. 2021, 2(4), 100898.
• Woodard, L.E.; Williams, F.M.; Jarrett, I.C.; and Wilson, M.H. "Functional analysis of the catalytic triad of the hAT-family transposon TcBuster." Plasmid. 2021, 114:102554.
• Beckermann, T.M.; Welch, R.C.; Williams, F.M.; Mortlock, D.P.; Sha, F.; Ikizler, T.A.; Woodard, L.E.; and Wilson, M.H. "CRISPR/Cas9 engineering of albino cystinuria Type A mice." Genesis. 2020, 58(5) e23357.

2015-2019

• Vanslambrouck, J.M.; Woodard, L.E.; Suhaimi, N.; Williams, F.M.; Howden, S.E.; Wilson, S.B.; Lonsdale, A.; Er, P.X.; Li, J.; Maksimovic, J.; Oshlack, A.; Wilson, M.H.; and Little, M.H. "Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1." Kidney Int., 2019, 95, 1153.
• Woodard, L.E.; Welch, R.C.; Veach, R.A.; Beckermann, T.M.; Sha, F.; Weinman, E.J.; Ikizler, T.A.; Tischfield, J.A.; Sahota, A.; Wilson, M.H. "Metabolic consequences of cystinuria." BMC Nephrol. 2019, 20, 227.
• Woodard, L.E.; Welch, R.C.; Williams, F.M.; Luo, W.; Cheng, J.; and Wilson, M.H. "Hydrodynamic renal pelvis injection for non-viral expression of proteins in the kidney." J. Vis. Exp., 2018, 1, 131.
• O’Neil, R.T.; Saha, S.; Veach, R.A.; Welch, R.C.; Woodard, L.E.; Rooney, C.M.; and Wilson, M.H. "Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo." Nat Commun, 2018, 9, 1325.
• Woodard, L.E.; Downes, L.M.; Lee, Y.C.; Kaja, A.; Terefe, E.S.; and Wilson, M.H. "Temporal self-regulation of transposition through host-independent transposase rodlet formation." Nucleic Acids Res., 2017, 45, 353–366.
• Luo, W.; Galvan, D.; Woodard, L. E.; Dorset, D.; Levy, S.; and Wilson, M.H. "Comparative analysis of chimeric ZFP-, TALE-, and Cas9-piggyBac transposases for integration into a single locus in human cells." Nucleic Acids Res. 2017, 45, 8411-8422.
• Woodard, L.E.; Cheng, J.; Welch, R.C.; Williams, F.M.; Luo, W.; Gewin, L.S.; and Wilson, M.H. "Kidney-specific transposon-mediated gene transfer in vivo." Scientific Reports. 2017, 7, 44904.
• Saha, S.; Woodard, L.E.; Charron, E.M.; Welch, R.C.; Rooney, C.M.; and Wilson, M.H. "Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells." Nucleic Acids Res. 2015, 43, 1770-82.
• Liang, M.; Woodard, L.E.; Liang, A.; Luo, J.; Wilson, M.H.; Mitch, W.E.; and Cheng, J. "Protective role of insulin-like growth factor-1 receptor in endothelial cells against unilateral ureteral obstruction-induced renal fibrosis." Am. J. Pathol. 2015, 185, 1234-50.

See Dr. Woodard's complete bibliography here.