Publications | Vanderbilt University Medical Center

*Indicates Senior/Corresponding Author

VDTRC team members are underlined.

Original Research Investigations

1. McNeil A, House DW, Mbala-Kingebeni P, Mbaya OT, Dodd LE, Cowen EW, Nussenblatt V, Bonnett T, Chen Z, Saknite I, Dawant BM, Tkaczyk ER.* “Counting Monkeypox Lesions in Patient Photographs: Limits of Agreement of Manual Counts and Artificial Intelligence,” Journal of Investigative Dermatology, in press
https://doi.org/10.1016/j.jid.2022.08.044

2. Parks K, Liu X, Reasat T, Khera Z, Baker LX, Chen H, Dawant BM, Saknite I, Tkaczyk ER,* “Non-expert markings of active chronic graft-versus-host disease photographs: optimal metrics of training effects," Journal of Digital Imaging, accepted for publication.

3. Saknite I, Patrinely JR, Zhao Z, Chen H, Kim TK, Jagasia M, Byrne M, Tkaczyk ER.* “Noninvasive Imaging of Leukocyte Adhesion and Rolling in Skin to Predict Outcomes after Hematopoietic Cell Transplantation,” JAMA Dermatology, 158(6):661-669, 2022. PMID: 35338704 NIHMSID: 1819485

4. McNeil A, Parks K, Liu X, Saknite I, Chen F, Reasat T, Wheless L, Dawant BM, Tkaczyk ER.* “Artificial Intelligence Recognition of Cutaneous Chronic Graft-versus-Host Disease by a Deep Learning Neural Network,” British Journal of Haematology, 197:e69-e93, 2022. PMID: 35322873 NIHMSID: 1794867 PMCID: PMC9197858 (embargo to 6/2023)

5. Saknite I, Gill M, Alessi-Fox C, Zwerner J, Lehman JS, Shinohara MM, Novoa RA, Chen H, Byrne M, Gonzalez S, Ardigo M, Tkaczyk ER*. “In Vivo Reflectance Confocal Microscopy of Cutaneous Acute Graft-Versus-Host Disease: Concordance with Histopathology and Interobserver Reproducibility of a Glossary with Representative Images,” Journal of the European Academy of Dermatology and Venereology, 36:1034–1044, 2022.PMID: 35175678 NIHMSID:1780772 PMCID: PMC9232909 (embargo to 7/2023)

6. Zhao Z, Patrinely JR, Saknite I, Byrne M, Tkaczyk ER*. “Guideline for In Vivo Assessment of Adherent and Rolling Leukocyte Counts in Human Skin Microvasculature via Reflectance Confocal Videomicroscopy,” Microcirculation, 28:e12725, 2021. https://doi.org/10.1111/micc.12725
PMID: 34409720 NIHMSID 1734440 PMCID: PMC8602735

7. Baker LX, Chen F, Cronin A, Chen H, Vain A, Jagasia M, Tkaczyk ER*. “Optimal biomechanical parameters for measuring sclerotic chronic graft-versus-host disease,” Journal of Investigative Dermatology Innovations, 1(3):100037, 2021. https://doi.org/10.1016/j.xjidi.2021.100037
PMID: 34790906 NIHMS1752697 PMCID: PMC8117134

8. Liu X, Parks K, Saknite I, Reasat T, Cronin A, Wheless L, Dawant B, Tkaczyk ER*. “Baseline photos and confident annotation improve automated detection of cutaneous graft-versus-host disease,” Clinical Hematology International, 3(3):108-115, 2021.
https://doi.org/10.2991/chi.k.210704.001 PMID: 34820616 PMCID: PMC8486973

9. Baker LX, Chen F, Ssempijja Y, Byrne M, Kim TK, Vain A, Jagasia M, Tkaczyk ER*. “Longitudinal tracking of skin dynamic stiffness to quantify evolution of sclerosis in chronic graft-versus-host disease,” Bone Marrow Transplantation, 56(4):989-991, 2021.
https://doi.org/10.1038/s41409-020-01158-w
PMID: 33279941 NIHMSID 1699349 PMCID: PMC8117134

10. Saknite I*, Zhao Z, Patrinely JR, Byrne M, Jagasia M, Tkaczyk ER. “Individual cell motion in healthy human skin microvasculature by reflectance confocal video microscopy,” Microcirculation, 27:e12621, 2020 (Cover article) https://doi.org/10.1111/micc.12621
PMID: 32304109 NIHMSID 1596478 PMCID: PMC7554192

11. Saknite I, Gill M, Alessi-Fox C, Byrne M, Jagasia M, Gonzàlez S, Tkaczyk ER*. “Features of cutaneous acute graft-versus-host disease by reflectance confocal microscopy,” British Journal of Dermatology, 181:828-831, 2019
https://doi.org/10.1111/bjd.17921
PMID: 30927259 PMCID: PMC6766422

12. Tkaczyk ER*, Coco J, Wang J, Chen F, Ye C, Jagasia M, Dawant B, Fabbri D. “Crowdsourcing to delineate skin affected by chronic graft-versus-host disease,” Skin Research and Technology, 25: 572-577, 2019. https://doi.org/10.1111/srt.12688 PMID: 30786065

13. Dellalana LE, Chen F, Vain A, Gandelman JS, Põldemaa M, Chen H, Tkaczyk ER*. “Reproducibility of the Durometer and Myoton Devices for Skin Stiffness Measurement in Healthy Subjects,” Skin Research and Technology, 25: 289-293, 2019 (Top 10% of downloaded articles in SRT in 2019)
DOI: 10.1111/srt.12646 PMID: 30414198

14. Chen F, Dellalana LE, Gandelman JS, Vain A, Jagasia MH, Tkaczyk ER*. “Noninvasive measurement of sclerosis in cutaneous cGVHD patients with the handheld device Myoton: a cross-sectional study,” Bone marrow transplantation, 54: 616-619, 2019
https://doi.org/10.1038/s41409-018-0346-7 PMID: 30287938

15. Gandelman JS, Zic J, Dewan AK, Lee SJ, Flowers M, Cutler C, Pidala J, Chen H, Jagasia MH, Tkaczyk ER*. “The Anatomic Distribution of Skin Involvement in Patients with Incident Chronic Graft-versus-Host Disease,” Biology of Blood and Marrow Transplantation, 25(2): 279-286, 2019.
DOI: 10.1016/j.bbmt.2018.09.007 PMID: 30219700

16. Tkaczyk ER*, Chen F, Wang J, Gandelman JS, Saknite I, Dellalana LE, Jagasia MH, Dawant BM. “Overcoming human disagreement assessing erythematous lesion severity on 3D photos of chronic graft-versus-host disease,” Bone marrow transplantation, 53:1356-1358, 2018
doi: 10.1038/s41409-018-0211-8 PMID: 29740182 PMCID: PMC6858843

Review Articles / Position Statements

17. Daneshjou R, Barata C, Betz-Stablein B, Celebi ME, Codella N, Combalia M, Guitera P, Gutman D, Halpern A, Helba B, Kittler H, Kose K, Liopyris K, Malvehy J, Seong HS, Soyer HP, Tkaczyk ER, Tschandl P, Rotemberg V*, “Checklist for Evaluation of Image-Based Artificial Intelligence Reports in Dermatology: CLEAR Derm Consensus Guidelines from the International Skin Imaging Collaboration Artificial Intelligence Working Group.” JAMA Dermatology, in press, 2021
doi:10.1001/jamadermatol.2021.4915 PMID: 34851366

18. Shakshouk H, Tkaczyk ER, Cowen EW, el‐Azhary RA, Hashmi SK, Kenderian SJ, Lehman JS*, “Methods to assess disease activity and severity in cutaneous chronic graft-versus-host disease: a critical literature review.” Transplantation and Cellular Therapy, in press, 2021
https://doi.org/10.1016/j.jtct.2021.05.030
PMID: 34107339 NIHMS1756796

19. Kitko CL*, Pidala J, Schoemans HM, Lawitschka A, Flowers ME, Cowen EW, Tkaczyk E, Farhadfar N, Jain S, Steven P, Luo ZK, Ogawa Y, Stern M, Yanik GA, Cuvelier GDE, Cheng GS, Holtan SG, Schultz KR, Martin PJ, Lee SJ, Pavletic SZ, Wolf D, Paczesny S, Blazar BR, Sarantopoulos S, Socie G, Greinix H, Cutler C. “National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIa. The 2020 Clinical Implementation and Early Diagnosis Working Group Report.” Transplant Cell Ther, 27(7):545-557, 2021.
PMID: 33839317 NIHMS1757220

20. Pidala J*, Kitko CL, Lee SJ, Carpenter P, Cuvelier G, Holtan SG, Flowers ME, Cutler C, Jagasia M, Gooley T, Palmer J, Randolph T, Levine JE, Ayuk F, Dignan F, Schoemans HM, Tkaczyk E, Farhadfar N, Lawitschka A, Schultz KR, Martin PJ, Sarantopoulos S, Inamoto Y, Socie G, Wolff D, Blazar BR, Greinix H, Paczesny S, Blazar BR, Pavletic S, Hill G. “National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIb. The 2020 Preemptive Therapy Working Group Report.” Transplant Cell Ther, 27(8):632-641, 2021.
PMID: 33836313

21. Tkaczyk ER*. “Innovations and developments in dermatologic non-invasive optical imaging and potential clinical applications.” Acta Dermato-Venereologica, Suppl. 218: 5-13, 2017 (invited)
doi: 10.2340/00015555-2717
PMID: 28676880

Patents

22. Tkaczyk ER, Vain A. VU18103P1 “Method and Device for Measuring or Determining at Least One Biomechanical Parameter of Soft Biological Tissues.” International Patent (PCT) Application No. 1904010.4 (United Kingdom Intellectual Property Office), Priority Date: March 22, 2019; PCT/US20/24194 filed with the US Patent Office on 3/23/2020

Book Chapters

23. Navarrete-Dechent C, Fischer C, Tkaczyk ER, Jain M. Principles of non-invasive diagnostic techniques in dermatology. In Rao B (Ed.), Moschella and Hurley's Dermatology, 4th Edition. Jaypee Brothers Medical Publishers 2020, pp 75-96

24. Curiel-Lewandrowski C, Balu M, Stemwedel CE, Chen SC, Ferris L, Gerami P, Green AC, Johnson M, Loescher LJ, Malvehy J, Marghoob AS, Martires K, Pellacani G, Petrie T, Puig S, Saknite I, Swetter S, Svendenhag P, Tkaczyk ER, Wisco O, Leachman SA (2018). Methods of Melanoma Detection. In A. Riker (Ed.), Melanoma: Comprehensive Management. New York: Springer 2018, pp 39-85
https://doi.org/10.1007/978-3-319-78310-9_4

Case Reports

25. Tadros J, Chastain C, Tkaczyk ER*. “Diffuse painful plaques in the setting of chronic lymphocytic leukemia,” Cutis 106(2), E18-E20, 2020.
doi:10.12788/cutis.0075 PMID: 32941567

26. Tadros J, Chastain C, Tkaczyk ER*. “Colonic and perianal ulceration exhibiting vacuolar interface dermatitis in the setting of HIV,” Clinical Case Reports 7, 1478-1480, 2019.
https://doi.org/10.1002/ccr3.2222 PMID: 31428371

27. Tadros J, Goodman S, Tkaczyk ER*. “Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis,” Dermatol Pract Concept 8(3), 184-187, 2018.
DOI: https://doi.org/10.5826/dpc.0803a07 PMID: 30116661

28. Riemenschneider K, Diiorio DA, Zic JA, Livingood MR, Fine JD, Powers JG, Zwerner JP, Tkaczyk ER*, “A case of drug-induced linear IgA bullous dermatosis in a patient with a vancomycin-impregnated cement spacer,” Cutis, 101(4), 293-296, 2018 (Cover article) PMID: 29763476

29. Dewan AK*, Dickerman D, Tkaczyk ER, Zwerner JP, Boyd A, Miller JL. “A rapidly growing facial mass: challenge,” American Journal of Dermatopathology, 39(6), 457-458, 2017
https://doi.org/10.1097/DAD.0000000000000473 PMID: 28291133

30. Riemenschneider K, Redenius R, Reese J, Fine JD, Weitkamp JH, Tkaczyk ER*, “Erythematous plaques and papules on a premature infant,” Journal of the American Academy of Dermatology, 76(4): e111-e112, 2017. http://dx.doi.org/10.1016/j.jaad.2016.08.038 PMID: 29081565

Proceedings (Refereed)

31. Wang J, Chen F, Tkaczyk ER, Dawant B, “Segmentation of Skin Lesions in Chronic Graft Versus Host Disease Photographs with Fully Convolutional Networks,” Proceedings of SPIE Medical Imaging 2018, 10575, 105750N-1 to 105750N-7, February 2018
doi: 10.1117/12.2293334

Abstracts (Refereed)

1. McNeil A, Parks K, Liu X, Saknite I, Chen F, Reasat T, Wheless L, Dawant BM, Tkaczyk ER, “Segmentation of cutaneous chronic graft-versus-host disease by a deep learning neural network,” poster presentation at the Society of Investigative Dermatology Annual Meeting, Portland OR, May 18-21, 2022

2. Saknite I, Gill M, Alessi-Fox C, Zwerner JP, Lehman JS, Shinohara MM, Novoa RA, Chen H, Byrne M, Gonzalez S, Ardigo M, Tkaczyk ER, “In vivo reflectance confocal microscopy of cutaneous acute graft-versus-host disease: concordance with histopathology and interobserver reproducibility of a glossary with representative images,” poster presentation at the Society of Investigative Dermatology Annual Meeting, Portland OR, May 18-21, 2022

3. Saknite I, Patrinely JR, Zhao Z, Chen H, Kim TK, Jagasia M, Byrne M, Tkaczyk ER, “Cutaneous leukocyte-endothelial interactions predict outcomes after hematopoietic cell transplantation,” poster presentation at the Society of Investigative Dermatology Annual Meeting, Portland OR, May 18-21, 2022

4. Saknite I, Patrinely JR, Zhao Z, Chen H, Kim TK, Jagasia M, Byrne M, Tkaczyk ER, “Bedside reflectance confocal videomicroscopy of immune cell motion in skin provides blood cancer insights,” oral presentation in Clinical and Translational Biophotonics, Optica Biophotonics Congress 2022, Fort Lauderdale FL, April 24-27, 2022

5. Saknite I, Patrinely JR, Zhao Z, Chen H, Kim TK, Jagasia M, Byrne M, Tkaczyk ER, “Cutaneous leukocyte-endothelial interactions predict outcomes after hematopoietic cell transplantation,” late-breaking abstract, oral presentation at the American Academy of Dermatology Annual meeting, Boston MA, March 24-29, 2022

6. Cronin A, Marks M, Phillips E, Saknite I, Tkaczyk E, “Photographic Documentation of The North American Therapeutics in Epidermal Necrolysis Syndrome (NATIENS) Study,” poster presentation at SJS/TEN 2021: Collaboration, Innovation and Community (virtual), August 28-29, 2021

7. Zhao Z, Patrinely JR, Saknite I, Byrne M, Jagasia M, Tkaczyk ER, “Inter-rater and intra-rater reliability of identifying leukocyte adhesion and rolling in upper dermal blood vessels via in vivo reflectance confocal video microscopy,” oral presentation a the 2nd World Congress of Confocal Microscopy (virtual), May 21-23, 2021

8. Cronin A, Saknite I, Hussain I, Bowden A, Tkaczyk ER, “Effect of distance, angle, and illumination on color in smartphone digital photos,” oral presentation paper 11618 in Photonics in Dermatology and Plastic Surgery, Photonics West BiOS, San Francisco CA, March 6-11, 2021

9. Saknite I, Kwun S, Liu X, Zhang K, Hood A, Chen F, Kangas L, Kukkonen A, Kortteisto P, Byrne M, Jagasia M, Tkaczyk ER, “Differentiation of erythematous and post-inflammatory pigment changes in cutaneous chronic graft-versus-host disease by hyperspectral imaging,” oral presentation paper 11618-15 in Photonics in Dermatology and Plastic Surgery, Photonics West BiOS, San Francisco CA, March 6-11, 2021

10. Glassman GE, Dellalana L, Tkaczyk ER, Esteve Manzanera I, Huang JY, Cronin A, Patrinely JR, Etemad S, Ridner S, Forte AJ, Al Kassis S, & Perdikis G. “The use of a Non-Invasive Myoton Device for Lymphedema Detection and Tracking; a Pilot Study,” virtual Plastic Surgery The Meeting ASPS-On Demand, October 9, 2020.

11. Baker LX, Byrne M, Martin P, Lee S, Chen H, Jagasia M, Tkaczyk ER, “Association of skin response in erythema and sclerosis with survival in chronic graft-versus-host disease” oral presentation 434 at the Society for Investigative Dermatology Annual Meeting Virtual Meeting, Scottsdale AZ, May 13-16, 2020 (Plenary Talk). Journal of Investigative Dermatology. 140 (7):S57, 2020

12. Baker LX, Chen F, Ssempijja Y, Dellalana L, Vain A, Jagasia M, Tkaczyk ER, “Direct mechanical measurements of skin to quantify evolution of sclerotic disease” Poster 867 at the Society for Investigative Dermatology Annual Meeting, Scottsdale AZ, May 13-16, 2020 (meeting cancelled). Journal of Investigative Dermatology. 140(7):S113, 2020

13. Parks K, Khera Z, Liu X, Reasat T, Baker LX, Jagasia MH, Dawant BM, Tkaczyk ER, “Redness has higher interrater reproducibility than body surface area in measuring extent of photographed cutaneous graft-versus-host disease" Poster 847 at the Society for Investigative Dermatology Annual Meeting, Scottsdale AZ, May 13-16, 2020 (meeting cancelled). Journal of Investigative Dermatology. 140(7):S110, 2020.

14. Patrinely JR, Saknite I, Zhao Z, Byrne M, Jagasia M, Tkaczyk ER, “Increased leukocyte pausing in the upper dermal microvasculature of cutaneous acute graft-versus-host disease patients by noninvasive reflectance confocal video microscopy” poster 842 at the Society for Investigative Dermatology Annual Meeting, Scottsdale AZ, May 13-16, 2020 (meeting cancelled). Journal of Investigative Dermatology. 140(7):S100, 2020.

15. Zhao Z, Patrinely JR, Saknite I, Byrne M, Jagasia M, Tkaczyk ER, “A guideline improves interrater reliability of assessing leukocyte motion in vivo in human skin” poster 838 at the Society for Investigative Dermatology Annual Meeting, Scottsdale AZ, May 13-16, 2020 (meeting cancelled). Journal of Investigative Dermatology. 140(7):S109, 2020.

16. Saknite I, Zhao Z, Patrinely JR, Byrne M, Jagasia M, Tkaczyk ER, “Study of individual cell motion in healthy human skin microcirculation by in vivo reflectance confocal video microscopy” poster presentation 18669 at the American Academy of Dermatology Annual meeting, Denver CO, March 20-24, 2020 (meeting cancelled). Journal of the American Academy of Dermatology. 83 (6):AB217, 2020

17. Patrinely JR, Saknite I, Zhao Z, Byrne M, Jagasia M, Tkaczyk ER, “Reflectance confocal video microscopy reveals altered cutaneous microcirculation in acute graft-versus-host disease: A cross-sectional study” oral presentation 18728 at the American Academy of Dermatology Annual meeting, Denver CO, March 20-24, 2020 (meeting cancelled). Journal of the American Academy of Dermatology. 83 (6):AB105, 2020

18. Wang LX, Chen F, Vain A, Ssempijja Y, Dellalana L, Zhang K, Hood A, Chen H, Jagasia M, Tkaczyk ER, “Reproducibility of Myoton and durometer devices to quantify skin stiffness and hardness in sclerotic chronic graft-versus-host disease” oral presentation 18038 at the American Academy of Dermatology Annual meeting, Denver CO, March 20-24, 2020 (meeting canceled). Journal of the American Academy of Dermatology. 83 (6):AB90, 2020

19. Ssempijja Y, Chen F, Wang LX, Vain A, Jagasia M, Tkaczyk ER, “Diagnostic potential of five different biomechanical parameters to detect sclerotic cutaneous graft-versus-host disease” oral presentation 18323 at the American Academy of Dermatology Annual meeting, Denver CO, March 20-24, 2020 (meeting canceled). Journal of the American Academy of Dermatology. 83 (6):AB98, 2020

20. Patrinely JR, Saknite I, Zhao Z, Byrne M, Jagasia M, Tkaczyk ER, “Noninvasive, Real-Time Microscopic Imaging Reveals Microvascular Changes in Cutaneous Acute Graft-Versus-Host Disease” oral presentation 71 at the Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, Orlando FL, February 19-23, 2020. Biology of Blood and Marrow Transplantation. 26(3):S53-54, 2020.

21. Zhao Z, Patrinely JR, Saknite I, Byrne M, Jagasia M, Tkaczyk ER, “Interrater Agreement of Non-Invasive Parameters Characteristic of Leukocyte-Endothelial Interactions in Upper Skin Microvasculature of Patients Post Allogeneic Hematopoietic Cell Transplant,” poster LBA9 at the Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, Orlando FL, February 19-23, 2020.

22. Saknite I, Byrne M, Jagasia M, Tkaczyk ER, “Confocal video microscopy reveals altered leukocyte-endothelial interactions in skin preceding acute graft-versus-host disease,” oral presentation paper 11211-14 in Photonics in Dermatology and Plastic Surgery, Photonics West BiOS, San Francisco CA, February 1-6, 2020.

23. Saknite I, Gill M, Alessi-Fox C, Zwerner J, Lehman J, Shinohara M, Novoa R, Byrne MT, Jagasia MH, Gonzalez S, Ardigo M, Tkaczyk ER, “Key Histopathology Features of Cutaneous Acute Graft-Versus-Host Disease Can be Detected Noninvasively,” poster 3278 at the American Society of Hematology Annual Meeting, Orlando FL, December 7-10, 2019. (Abstract Achievement Award Winner)
Blood 134 (Suppl 1): 3278-3278, 2019.

24. Saknite I, Byrne MT, Jagasia MH, Tkaczyk ER, “Noninvasive Microscopic Imaging Reveals Increased Leukocyte Adhesion and Rolling in Skin of Acute Graft-Versus-Host Disease Patients Compared to Post-Transplant Controls,” poster 4533 at the American Society of Hematology Annual Meeting, Orlando FL, December 7-10, 2019. Blood 134 (Suppl 1): 4533, 2019

25. Chen F, Wang LX, Ssempijja Y, Cronin A, Chen H, Vain A, Jagasia MH, Tkaczyk ER, “Diagnostic Potential of Five Different Biomechanical Parameters to Detect Sclerotic Cutaneous Graft-Versus-Host Disease,” poster 2002 at the American Society of Hematology Annual Meeting, Orlando FL, December 7-10, 2019. (Abstract Achievement Award Winner)
Blood 134 (Suppl 1): 2002-2002, 2019

26. Chen F, Wang LX, Vain A, Ssempijja Y, Dellalana L, Zhang K, Hood A, Chen H, Jagasia MH, Tkaczyk ER, “Interobserver Reproducibility of the Myoton and Durometer Devices to Measure Skin Stiffness and Hardness in Chronic Cutaneous Graft-Versus-Host Disease Patients,” poster 4515 at the American Society of Hematology Annual Meeting, Orlando FL, December 7-10, 2019. Blood 134 (Suppl 1): 4515, 2019

27. Tkaczyk ER, Saknite I, Byrne M, Jagasia M, “Cutaneous acute graft-versus-host disease assessment by confocal video microscopy,” oral presentation in “Skin imaging other than dermatoscopy,” World Congress of Dermatology, Milan, Italy, June 10-15, 2019 (AAD scholarship winning abstract)

28. Saknite I, Gill M, Alessi-Fox C, Zwerner J, Lehman J, Shinohara M, Novoa R, Byrne MT, Jagasia MH, Gonzalez S, Ardigo M, Tkaczyk ER, “Reflectance confocal microscopy of acute graft-versus-host disease: correlation to histopathology and interrater reproducibility,” late-breaking poster abstract 410, World Congress of Dermatology, Milan, Italy, June 10-15, 2019

29. Chen F, Jagasia MH, Vain A, Tkaczyk ER, “Accuracy of biomechanical assessment of sclerotic chronic graft-versus-host disease” late-breaking poster abstract 342, World Congress of Dermatology, Milan, Italy, June 10-15, 2019

30. Saknite I, Byrne M, Jagasia M, Tkaczyk ER, “Leukocyte dynamics in cutaneous acute graft-versus-host disease by noninvasive laser confocal video microscopy: a cross-sectional pilot study,” oral presentation paper 10885-13 in Optical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics, Photonics West BiOS, San Francisco CA, February 2-7, 2019

31. Saknite I, Byrne M, Tkaczyk ER, “Characterization of individual cell motion in human skin capillaries by noninvasive reflectance confocal video microscopy,” oral presentation paper 10877-11 in Dynamics and Fluctuations in Biomedical Photonics XVI, Photonics West BiOS, San Francisco CA, February 2-7, 2019

32. Runnel T, Hermann H, Urgard E, Aab A, Abram K, Sahmatova L, Kaldvee B, Tkaczyk ER, Akdis CA, Kingo K and Rebane A, “miR-10a has capacity to control keratinocyte proliferation, inflammatory responses and extracellular matrix formation in atopic dermatiti,” European Academy of Allergy and Clinical Immunology (EAACI) Congress, Munich, Germany, May 26-30, 2018. Allergy 73: 830, 2018

33. Runnel T, Hermann H, Urgard E, Aab A, Abram K, Sahmatova L, Kaldvee B, Tkaczyk ER, Akdis CA, Kingo K and Rebane A, “miR-10a modulates keratinocyte responses in atopic dermatitis,” poster LB1556 at the International Investigative Dermatology (IID) Meeting, Orlando FL, May 16-19, 2018. Journal of Investigative Dermatology 138 (9): B15, 2018

34. Chen F, Dellalana L, Saknite I, Gandelman J, Vain A, Vaughan L, Clifton C, Logue M, Byrne M, Kassim A, Savani B, Jagasia M, Tkaczyk ER, “Sclerotic chronic graft-versus-host disease severity can be assessed via biomechanical properties of skin,” Bone Marrow Transplant Tandem Meetings (CIBMTR and ASBMT), Salt Lake City UT, February 21-25, 2018. Biology of Blood and Marrow Transplantation 24 (3): S198-S199, 2018

Invited Presentations and Abstracts-International

+Lectures providing Continuing Medical Education (CME) credits are marked with an asterisk.

35. Saknite I, Patrinely JR, Zhao Z, Kwun S, Zhang K, Hood A, Chen F, Kangas L, Kukkonen A, Kortteisto P, Kim TK, Beeghly-Fadiel A, Byrne M, Spigulis J, Tkaczyk ER, Light-based technologies for clinical impact: hyperspectral imaging and reflectance confocal videomicroscopy of skin. Developments in Optics and Communications (virtual). April 21-22, 2022.

36. Saknite I, Tkaczyk ER, Biophotonics for patient care: building a translational research team at a medical center in the United States. IX International Physics Conference in honor of F. Pianca (virtual). December 22-23, 2021.

37. Tkaczyk ER, 3D Imaging and Artificial Intelligence to Stage and Follow SJS/TEN. SJS/TEN 2021: Collaboration, Innovation and Community (virtual). August 28-29, 2021.

38. Saknite I, Tkaczyk ER, Acute GVHD, an update and discussion comparing inter-rater reliability to detect features using RCM versus histopathology. The 2nd World Congress of Confocal Microscopy (virtual). May 21-23, 2021.

39. Saknite I, Zhao Z, Patrinely JR, Byrne M, Tkaczyk ER, Tracking leukocyte-endothelial interactions in the first 100 days post hematopoietic stem cell transplantation. The 2nd World Congress of Confocal Microscopy (virtual). May 21-23, 2021.

40. Saknite I, Zhao Z, Patrinely JR, Byrne M, Tkaczyk ER, “Post-transplant leukocyte motion in human skin microvasculature by noninvasive reflectance confocal video microscopy,” Optical Society of America Biophotonics Congress: Biomedical Optics, Fort Lauderdale FL, April 20-23, 2020

41. Saknite I, Zhao Z, Patrinely JR, Byrne M, Jagasia M, Tkaczyk ER, “Noninvasive visualization of individual cell motion in human skin microvasculature by reflectance confocal video microscopy,” OSA Traveling Lecturer Program talk at the Federal University of ABC, Santo Andre, Brazil, November 29, 2019

42. +Tkaczyk ER, “Emerging imaging modalities for melanoma.” Invited talk in the Symposium “Melanoma: The Future Is Now,” 77th Annual Meeting of the American Academy of Dermatology, Washington DC, March 1-5, 2019

43. Saknite I and Tkaczyk ER, “RCM for GvHD evaluation,” World Congress of Confocal Microscopy, Rome, Italy, October 18-20, 2018.

44. Tkaczyk ER, “Non-morphologic insight into the skin : optical and electrical spectroscopy,” 5th World Congress of Dermoscopy, Thessaloniki, Greece, June 14-16, 2018

45. Chen F, Wang J, Saknite I, Patterson MD, Fabbri D, Dawant B, Jagasia MH, Tkaczyk ER, “Bringing biophotonics to dermatology patients: experiences from a new cutaneous imaging clinic,” Optical Society of America Biophotonics Congress: Biomedical Optics, Hollywood FL, April 4-6, 2018

46. +Tkaczyk ER, “Noninvasive imaging.” Invited talk in the Symposium “Role of dermatologist in management of skin disease in solid organ transplant recipients,” 76th Annual Meeting of the American Academy of Dermatology, San Diego CA, February 16-20, 2018

47. +Tkaczyk ER, “Noninvasive imaging.” Invited talk in the Symposium “Role of dermatologist in management of skin disease in solid organ transplant recipients,” 75th Annual Meeting of the American Academy of Dermatology, Orlando FL, March 3-7, 2017

48. +Tkaczyk ER, “Biophotonics in dermatology.” Invited talk in the Symposium “New and emerging technologies in dermatology,” 75th Annual Meeting of the American Academy of Dermatology, Orlando FL, March 3-7, 2017

Invited Presentations-National

+Lectures providing Continuing Medical Education (CME) credits are marked with an asterisk.

49. +Tkaczyk ER, “Artificial intelligence photo analysis to measure inflammatory skin disease,” Mayo Clinic Dermatology Research Symposium, Rochester MN, March 14, 2022 (Keynote Speaker and Harold O. Perry named visiting professor and lecturer)

50. Tkaczyk ER, “Development of imaging and mechanical assessments of cutaneous graft-versus-host disease,” Fred Hutchinson Cancer Center Long Term Followup Unit Seminar, Seattle WA, January 25, 2022

51. Saknite I, Patrinely JR, Zhao Z, Chen H, Beeghly-Fadiel A, Kim TK, Jagasia M, Byrne M, Tkaczyk ER, “Noninvasive Imaging of Leukocyte Adhesion and Rolling in Skin to Predict Outcomes after Hematopoietic Cell Transplantation: a Prospective Cohort Study,” American Society for Clinical Investigation Annual Meeting, Chicago, IL, April 8-10, 2022

52. +Saknite I, Zhao Z, Patrinely JR, Byrne M, Tkaczyk ER, “Emerging use of optical imaging for assessing graft-versus-host disease,” Annual Conference of the American Society for Laser Medicine and Surgery, May 15-16, 2021

53. Tkaczyk ER, “Skin imaging as a source of clinical biomarkers after stem cell transplant,” Cutaneous Immunobiology Symposium of the Vanderbilt Center for Immunobiology, Nashville, Tennessee, March 12, 2021

54. Saknite I, Kwun S, Patrinely JR, Zhao Z, Zhang K, Hood A, Chen F, Liu X, Kangas L, Kukkonen A, Kortteisto P, Byrne M, Jagasia M, Tkaczyk ER, “Hyperspectral imaging and videomicroscopy of skin in patients after a stem cell transplant,” Washington State University, Physics and Astronomy Colloquium, Pullman WA, February 11, 2021

55. +Tkaczyk ER, Department of Dermatology Grand Rounds Lecture, Mayo Clinic Arizona Department of Dermatology, Scottsdale AZ, May 13, 2020 (invited; cancelled due to COVID19)
56. Tkaczyk ER, University of Arizona Cancer Imaging Program meeting, Tuscon AZ, May 12, 2020 (invited; cancelled due to COVID19)

57. +Saknite I, Zhao Z, Patrinely JR, Byrne M, Tkaczyk ER, “Emerging use of optical imaging for assessing graft-versus-host disease,” Annual Conference of the American Society for Laser Medicine and Surgery, Phoenix AZ, April 29 - May 3, 2020 (meeting cancelled)

58. Saknite I, Byrne M, Jagasia M, Tkaczyk ER, “Leukocyte dynamics in human skin capillaries by noninvasive reflectance confocal microscopy,” University of California Irvine, Beckman Laser Institute Seminar, Irvine CA, February 8, 2019