Deepak Gupta, MD, MSCI, is an Associate Professor of Medicine, Director of the Vanderbilt Translational and Clinical Cardiovascular Research Center, and Director of the Vanderbilt Heart Imaging Core Lab in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center. His research focuses on differential susceptibility to heart failure and its outcomes with particular focus on the natriuretic peptide-cGMP system and sodium handling.
Dr. Gupta's clinical research program has the following major aims: 1) to understand mechanisms for the development of and outcomes in hypertension and its related sequelae, including heart failure, 2) to understand the natriuretic peptide-cGMP system, 3) to understand cardiac structure and function in relation to cardiovascular risk factors and disease, and 4) to understand differences in susceptibility to cardiometabolic risk and cardiovascular disease. His group studies cardiovascular disease through several approaches including Clinical Research Center-based physiologic studies, epidemiologic cohorts, and clinical trials.
Sub-specialization in cardiology allows Dr. Gupta to identify clinical issues facing patients, which motivates his research. As a physician-scientist, he leads a clinical research program that provides an environment through which he mentors trainees in research with the goal of developing physician-scientists. Clinically, he attends on inpatient cardiology services, cares for patients through his dedicated heart failure with preserved ejection fraction clinic, and reads echocardiograms.
Key Research Areas
Cardiovascular Epidemiology
Cardiovascular Imaging
Heart Failure
Women's Cardiovascular Health
Grants
- 2021-2026: NHLBI Improving diagnostic accuracy for acute heart failure
- 2019-2025: NHLBI Dietary sodium, inflammation, and salt sensitivity of blood pressure
- 2016-2021: NHLBI Tissue sodium, inflammation, and blood pressure
- 2016-2021: NHLBI The natriuretic peptide system in African Americans
- 2020-2025: NHLBI Improving Pulmonary Congestion Assessment in HF
- 2020-2025: NHLBI Epidemiology of Cardiac Structure and Function in African Caribbeans: The Tobago Heart Study
- 2020-2025: NHLBI Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition
- 2021-2025: NHLBI Long-Term Cardiovascular Sequelae of Cancer Immunotherapies
- 2015-2025: NIA Memory and Aging Project 2020-2025: NHLBI Gut microbial metabolites and risk of coronary heart disease: a prospective, multiethnic, metabolomic study
- 2015-2020: Astellas Heart Failure with Preserved Ejection: Myocardial Perfusion, Oxidative Metabolism, and Fibrosis
Honors and Awards
- 2024 VUMC Biomedical Clinical Impact Research Prize
- 2020 Fellow of the American Heart Association, Council on Genomic and Precision Medicine
- 2018 Multi-Ethnic Study of Atherosclerosis, Outstanding Investigator Award
- 2017 Cardiology Today's Next Gen Innovators
- 2015 American Heart Association Elizabeth Barrett-Connor Young Investigator Finalist
- 2015 Northwestern Cardiovascular Young Investigator Forum Finalist
- 2015 Cardiology Outstanding Teacher of the Year Award, Vanderbilt University
- 2014 Non-Invasive Cardiology Teacher of the Year Award, Vanderbilt University