Featured Publications

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  1. Increased Ripk1-mediated bone marrow necroptosis leads to myelodysplasia and bone marrow failure in mice. Wagner PN, Shi Q, Salisbury-Ruf CT, Zou J, Savona MR, Fedoriw Y, Zinkel SS.
  2. Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study. Salisbury-Ruf CT, Bertram CC, Vergeade A, Lark DS, Shi Q, Heberling ML, Fortune NL, Okoye GD, Jerome WG, Wells QS, Fessel J, Moslehi J, Chen H, Roberts LJ 2nd, Boutaud O, Gamazon ER, Zinkel SS.​
  3. Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain. Vergeade A, Bertram CC, Bikineyeva AT, Zackert WE, Zinkel SS, May JM, Dikalov SI, Roberts LJ 2nd, Boutaud O.
  4. Revisiting the case for genetically engineered mouse models in human myelodysplastic syndrome research.Zhou T, Kinney MC, Scott LM, Zinkel SS, Rebel VI.
  5. In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells. Ratliff M, Alter S, McAvoy K, Frasca D, Wright JA, Zinkel SS, Khan WN, Blomberg BB, Riley RL.​
  6. MTG16 contributes to colonic epithelial integrity in experimental colitis. Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, Williams AD, Fisher MA, Zinkel SS, Peek RM Jr, Wilson KT, Hiebert SW.
  7. Rejuvenating Bi(d)ology. Zinkel SS, Yin XM, Gross A.​
  8. The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm-/- mice. Biswas S, Shi Q, Wernick A, Aiello A, Zinkel SS.
  9. Bid protects the mouse hematopoietic system following hydroxyurea-induced replicative stress. Liu Y, Aiello A, Zinkel SS.
  10. Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation. Yin H, Vergeade A, Shi Q, Zackert WE, Gruenberg KC, Bokiej M, Amin T, Ying W, Masterson TS, Zinkel SS, Oates JA, Boutaud O, Roberts LJ 2nd.
  11.  BID binds to replication protein A and stimulates ATR function following replicative stress. Liu Y, Vaithiyalingam S, Shi Q, Chazin WJ, Zinkel SS.​
  12. Proapoptotic Bid mediates the Atr-directed DNA damage response to replicative stress. Liu Y, Bertram CC, Shi Q, Zinkel SS.
  13.  A role for proapoptotic Bax and Bak in T-cell differentiation and transformation. Biswas S, Shi Q, Matise L, Cleveland S, Dave U, Zinkel S.
  14. Bid regulates the pathogenesis of neurotropic reovirus. Danthi P, Pruijssers AJ, Berger AK, Holm GH, Zinkel SS, Dermody TS.
  15. Investigation of the proapoptotic BCL-2 family member bid on the crossroad of the DNA damage response and apoptosis. Zinkel SS.
  16. Bid plays a role in the DNA damage response. Zinkel SS, Hurov KE, Gross A.
  17. BCL2 family in DNA damage and cell cycle control. Zinkel S, Gross A, Yang E.
  18. A role for proapoptotic BID in the DNA-damage response. Zinkel SS, Hurov KE, Ong C, Abtahi FM, Gross A, Korsmeyer SJ 
  19. Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, Korsmeyer SJ.
  20.  Proapoptotic BID is required for myeloid homeostasis and tumor suppression. Zinkel SS, Ong CC, Ferguson DO, Iwasaki H, Akashi K, Bronson RT, Kutok JL, Alt FW, Korsmeyer SJ.
  21. Function of BID -- a molecule of the bcl-2 family -- in ischemic cell death in the brain. Plesnila N, Zinkel S, Amin-Hanjani S, Qiu J, Korsmeyer SJ, Moskowitz MA. 
  22. BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia. Plesnila N, Zinkel S, Le DA, Amin-Hanjani S, Wu Y, Qiu J, Chiarugi A, Thomas SS, Kohane DS, Korsmeyer SJ, Moskowitz MA.
  23. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Yin XM, Wang K, Gross A, Zhao Y, Zinkel S, Klocke B, Roth KA, Korsmeyer SJ 
  24. Death and survival signals determine active/inactive conformations of pro-apoptotic BAX, BAD, and BID molecules. Korsmeyer SJ, Gross A, Harada H, Zha J, Wang K, Yin XM, Wei M, Zinkel S.
  25. Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. Wang X, Zinkel S, Polonsky K, Fuchs E.
  26. Skin cancer and transgenic mice. Zinkel S, Fuchs E.
  27.  Identification of a negative regulatory element that inhibits c-mos transcription in somatic cells. Zinkel SS, Pal SK, Szeberényi J, Cooper GM.
  28.  c-mos expression in mouse oocytes is controlled by initiator-related sequences immediately downstream of the transcription initiation site. Pal SK, Zinkel SS, Kiessling AA, Cooper GM.
  29. Catabolite activator protein-induced DNA bending in transcription initiation. Zinkel SS, Crothers DM.
  30. Comparative gel electrophoresis measurement of the DNA bend angle induced by the catabolite activator protein. Zinkel SS, Crothers DM.
  31. DNA bend direction by phase sensitive detection Zinkel SS, Crothers DM.