Featured Publications


See Dr. Huize Pan's full bibliography here and publications in PubMed here.​​​​​​​

1. Pan H*, Ho SE, Xue C, Cui J, Johanson QS, Sachs N, Ross LS, Li F, Solomon RA, Connolly ES, Patel VI, Maegdefessel L, Zhang H, Reilly MP*. Atherosclerosis Is a Smooth Muscle Cell-Driven Tumor-Like Disease. Circulation. 2024 Apr 30. doi: 10.1161/CIRCULATIONAHA.123.067587. PMID: 38686559. *co-corresponding authors.


2. Pan H*, Ho SE, Xue C, Cui J, Ross LS, Reilly MP*. Retinoic acid signaling modulates smooth muscle cell phenotypic switching in atherosclerosis through epigenetic regulation of gene expression. bioRxiv, 2022. doi.org/10.1101/2022.11.09.515888. *co-corresponding authors.


3. Pan H1*, Xue C1, Auerbach BJ1, Fan J, Bashore AC, Cui J, Yang DY, Trignano SB, Liu W, Shi J, Ihuegbu CO, Bush EC, Worley J, Vlahos L, Laise P, Solomon RA, Connolly ES, Califano A, Sims PA, Zhang H, Li M, Reilly MP*. Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human. Circulation. 2020 Nov 24;142(21):2060-2075. doi: 10.1161/CIRCULATIONAHA.120.048378. PMID: 32962412. PMCID: PMC8104264. 1co-first authors, *co-corresponding authors.


4. Li X, Wang K, Lyu Y, Pan H, Zhang J, Stambolian D, Susztak K, Reilly MP, Hu G, Li M. Deep learning enables accurate clustering with batch effect removal in single-cell RNA-seq analysis. Nature Communications. 2020 May 11;11(1):2338. doi: 10.1038/s41467-020-15851-3. PMID: 32393754. PMCID: PMC7214470.


 5. Pan H, Reilly MP. A protective smooth muscle cell transition in atherosclerosis. Nature Medicine. 2019 Aug;25(8):1194-1195. doi: 10.1038/s41591-019-0541-0. PMID: 31359004. PMCID: PMC7307968.


6. Pan H1, Guan D1, Liu X1, Li J, Wang L, Wu J, Zhou J, Zhang W, Ren R, Zhang W, Li Y, Yang J, Hao Y, Yuan T, Yuan G, Wang H, Ju Z, Mao Z, Li J, Qu J, Tang F, Liu GH. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Research. 2016 Feb;26(2):190-205. doi: 10.1038/cr.2016.4. PMID: 26768768. PMCID: PMC4746611. 1co-first authors.


7. Pan H1, Cai N1, Li M1, Liu GH, Izpisua Belmonte JC. Autophagic control of cell 'stemness'. EMBO Mol Med. 2013 Mar;5(3):327-31. doi: 10.1002/emmm.201201999. PMID: 23495139; PMCID: PMC3598074. 1co-first authors.


8. Pan H1, Zhang W1, Zhang W, Liu GH. Find and replace: editing human genome in pluripotent stem cells. Protein Cell. 2011 Dec;2(12):950-6. doi: 10.1007/s13238-011-1132-0. PMID: 22173708; PMCID: PMC4875250. 1co-first authors.