Baroreflex Failure

What it is: A rare disorder of the autonomic nervous system in which the baroreflex (the body’s blood pressure control system) does not work properly. This leads to an inability to maintain stable blood pressure and heart rate, especially in response to stress, position changes, or everyday activities.

Key Symptoms

  • Sudden episodes of very high blood pressure (hypertensive surges).
  • Periods of low blood pressure, especially at rest or when standing.
  • Abnormal heart rate changes (too fast or too slow).
  • Lightheadedness or fainting.
  • Headaches, flushing, or sweating during blood pressure spikes.
Dizzy female

What patients may notice

  • Feeling “fine one moment and unwell the next” due to rapid blood pressure swings.
  • Severe headaches or pounding heartbeat during high blood pressure episodes.
  • Dizziness, weakness, or near fainting, especially when standing or after activity.
  • Symptoms triggered by stress, strong emotions, pain, or exertion.
  • Difficulty predicting or controlling symptoms, which can be frustrating and disruptive.