Ulcerative Colitis

Ulcerative Colitis is a chronic inflammatory condition that causes long-lasting inflammation and ulcers in the inner lining of the large intestine or colon. Ulcerative colitis differs from Crohn's disease in that Crohn's can affect any part of the Gastrointestinal (GI) tract, whereas ulcerative colitis affects only the colon. 

Most patients with ulcerative colitis have mild to moderate symptoms. If left untreated however, these symptoms can lead to other, more serious complications. 

While there is a wide range of severity and symptoms among patients with ulcerative colitis, common symptoms include:

  • rectal bleeding
  • abdominal pain and cramping
  • persistent diarrhea
  • loose and more urgent bowel movements
  • loss of appetite
  • fatigue

Fortunately, there are several treatment options available for people living with Ulcerative colitis. While there is no known cure, these treatments work to reduce the signs and symptoms of the disease and introduce long-term remission. 

If you have not had success with available treatment options, search the clinical trials listed below and talk with your doctor about clinical trials you may be eligible for. Scientists and researchers are continually working to find ways to improve the quality of life for people living with Ulcerative Colitis.

At Vanderbilt's GI Clinical Research Enterprise, we are dedicated to finding a solution that works for you.