Title and Department
Associate Professor of Medicine
Department of Medicine
Infectious Diseases
Professional bio

John Koethe, MD, MSCI, is an Associate Professor in Vanderbilt University Medical Center's Division of Infectious Diseases, and a physician-scientist pursuing clinical and translational research on the role of the immune system in the development of cardiovascular and metabolic diseases.

He completed his medical degree at Yale University followed by a residency in internal medicine at Johns Hopkins Hospital. Dr. Koethe came to Vanderbilt as an infectious diseases fellow in 2007 and joined the faculty in 2010. He was a National Institutes of Health Fogarty International Clinical Research Fellow at the Centre for Infectious Diseases Research in Zambia, and he subsequently completed training in clinical research study design, methods, and biostatistics through the Vanderbilt Master of Science in Clinical Investigation Program.

Dr. Koethe is is a board certified infectious diseases physician and the principal investigator of National Institutes of Health R01 and Veterans Affairs Merit grants to explore the role of the adipose tissue immune environment in the development of metabolic disease, and whether excess accumulation of fat in skeletal muscle promotes mitochondrial dysfunction and insulin resistance. Dr. Koethe has a strong commitment to the career development of early career investigators in infectious diseases and metabolic research.

He is the Director of the Developmental Core of the Tennessee Center for AIDS Research, which is responsible for administering pilot grant awards and mentoring young investigators and those new to HIV research, as well as Program Director of the NHLBI-supported Vanderbilt Scholars in HIV and Heart, Lung, Blood, and Sleep Research (V-SCHoLARS, K12), which supports 5 post-doctoral trainees for 2-3 years of mentored clinical and translational research on the intersection of HIV and HLBS conditions. Dr. Koethe currently sees patients at the Veterans Affairs Tennessee Valley Health Care System Nashville campus.