Ming Jiang, MD, PhD, is a biomedical research scientist with extensive expertise in establishment and characterization of primary culture cells, immortalized cell lines, 3D-organoid culture, patient-derived xenografting (PDX), and tissue recombination-xenografting (TRX) models in prostate, bladder, colorectal, and lung organs.
Dr. Jiang’s general interests include functional dissection of nuclear receptor signaling pathways in pathogenesis, carcinogenesis, and cancer progression using novel in vitro and in vivo translational preclinical research models.
His research interests are focused on three main topics: 1) cross-talk of the Arachidonic Acid/COXs/LOXs/PPARgamma signaling pathways in pathogenesis and carcinogenesis; 2) functional remodeling of human normal, benign, and cancerous glandular tissues in a combination of 3D-organoid culture and tissue recombination-xenografting (TRX) mouse models based on epithelial-stromal interactions, tumor microenvironment, and immuno-oncology; and 3) establishment of a spontaneous human cancer-mouse multi-organ including bone metastases model.