Renal Translational Pathology Workshop
Three-day intensive workshop that focuses on mouse kidney pathology, including training in quantitative and qualitative analyses of different renal pathologies and stains
The Vanderbilt O'Brien Kidney Center (VOKC) is organizing a 2-day, comparative renal pathology workshop with didactic and hands-on training in qualitative and quantitative renal pathology February 23rd and 24th 2023 at Vanderbilt University Medical Center in Nashville. Drs. Agnes Fogo and Haichun Yang from the Division of Renal Pathology at Vanderbilt University Medical Center have developed a virtual slide-based workshop to train pre-clinical investigators on the fundamentals of human and experimental renal pathology, focusing on similarities and differences between human disease and mouse models used to study these human diseases. They will be assisted by Dr. Charles Jennette from the Department of Pathology at the University of North Carolina, Chapel Hill, Dr. Mark de Caestecker and Dr. Raymond Harris from the Nephrology Division at Vanderbilt University Medical Center, who will be providing additional content expertise. The focus of the workshop will be to train investigators to understand the relevance of experimental models of human disease and to understand how to interpret and quantify histological findings using these models so they can bring this expertise back to their own institutions.
Four topic areas (diabetic nephropathy; focal segmental glomerular sclerosis; acute kidney injury; and crescentic kidney disease) will be covered, with the goal to train investigators to recognize:
- patterns of renal injury
- similarities and differences between human and mouse models of kidney disease, as well as species and strain differences in renal pathology seen using different experimental models; and
- to be able to quantify cell specific pathologic changes using the appropriate histological staining. The format of the workshop will include lectures covering basic background about the human diseases, the mouse models used, the quantitative methods used to evaluate them, alternating with hands-on interactive training using computer-based virtual slides to illustrate the pathologies being discussed. Each student will be required to bring their own laptop.
The format of the workshop will include lectures covering basic background about the human diseases, the mouse models used, the quantitative methods used to evaluate them, alternating with hands-on interactive training using computer-based virtual slides to illustrate the pathologies being discussed.
Reasons to attend:
- You study mouse renal disease models, but have not been trained how to evaluate different renal pathologies, and do not have expertise at your institution to help read and quantify you tissue sections
- You have new personnel joining your lab who need to be brough up to speed to study mouse kidney injury models
- You know a little but want to know more about different mouse renal pathologies and their relationship with the human diseases they are modeling
Each student will be required to bring their own laptop.
* Each attendee will have one computer loaded with human and mouse virtual slides and software (image J, Aperio Image Scope). Background of individual human disease or mouse model and working sheet will also be provided.